"Separating contenders from
pretenders in breast cancer"

-- ASCO Post

"Blazes a trail in breast cancer"

-- Nature Biotechnology

"A glimpse into the future of
phase II drug development?"

-- NEJM

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Featured News

Upcoming FDA workshop: "Clinical Trials to Optimize Outcomes in Early Breast Cancer"

Announcement

September 14, 2018

I-SPY 2, an Innovative Clinical Trial Model that is Revolutionizing the Treatment of Early Stage, High-Risk Breast Cancer

Press Release

September 12, 2018

Advanced MRI methods tested in I-SPY 2 may improve monitoring and prediction of treatment response

Announcement

September 7, 2018

-- more news --

What is I-SPY?

The I-SPY series of trials are changing the way new treatments are developed for breast cancer, helping make available new, better and more personalized treatments, faster. At the heart of the I-SPY program is the ground-breaking I-SPY 2 platform trial for neoadjuvant treatment of locally advanced breast cancer.

1300

patients enrolled

16

agents completed
evaluation since 2010

3

agents received
accelerated approval

World-class science requires world-class scientists

Meet some of our team

Associate Professor

University of Minnesota

Professor of Medicine, Director of Breast Cancer Translational Research

Yale University

Julie Wulfkuhle

Research Professor

George Mason University

Professor of Medicine and Pharmacology

University of Minnesota

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I-SPY is supported by:

I-SPY Sponsor:
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Quantum Leap Healthcare Collaborative