Quantum Leap Healthcare Collaborative
search

"Separating contenders from
pretenders in breast cancer"

-- ASCO Post

"Blazes a trail in breast cancer"

-- Nature Biotechnology

"A glimpse into the future of
phase II drug development?"

-- NEJM
Close
Close
Close
Close
Close
Close
I-SPY Email List Sign-up

Thank you, your subscription is activated.

If you change your mind, you can unsubscribe at any time.
Oops! Something went wrong while submitting the form.
Close
Close
I-SPY  PATIENT INFORMATION SITE. Visit: www.ispypatient.org
Perlmutter J, Brain S, Brown T, et al.
Advocate involvement in Clinical Trials: Lessons from the Patient-centric I-SPY2 Breast Cancer Trial
.
Med Res Arch
11 (7.2)
:
, 
2023
.
abstract
pdf
doi
Perlmutter J, Brain S, Brown T, et al.
Advocate involvement in Clinical Trials: Lessons from the Patient-centric I-SPY2 Breast Cancer Trial
. In 
 (Eds.), 
Med Res Arch
11 (7.2)
(
); pp.
, 
2023
.
abstract
pdf
link
Boughey JC, Yu H, Dugan CL, et al.
Changes in Surgical Management of the Axilla Over 11 Years – Report on More Than 1500 Breast Cancer Patients Treated with Neoadjuvant Chemotherapy on the Prospective I-SPY2 Trial
.
Ann Surg Oncol
(published online)
:
1-10
, 
2023
.
abstract
pdf
doi
Boughey JC, Yu H, Dugan CL, et al.
Changes in Surgical Management of the Axilla Over 11 Years – Report on More Than 1500 Breast Cancer Patients Treated with Neoadjuvant Chemotherapy on the Prospective I-SPY2 Trial
. In 
 (Eds.), 
Ann Surg Oncol
(published online)
(
); pp.
1-10
, 
2023
.
abstract
pdf
link
Mukhtar RA, Chau H, Woriax H, et al.
Breast Conservation Surgery and Mastectomy have Similar Locoregional Recurrence Following Neoadjuvant Chemotherapy: Results from 1,462 Patients on the Prospective, Randomized I-SPY2 Trial
.
Ann Surg
(published ahead of print)
:
, 
2023
.
abstract
pdf
doi
Mukhtar RA, Chau H, Woriax H, et al.
Breast Conservation Surgery and Mastectomy have Similar Locoregional Recurrence Following Neoadjuvant Chemotherapy: Results from 1,462 Patients on the Prospective, Randomized I-SPY2 Trial
. In 
 (Eds.), 
Ann Surg
(published ahead of print)
(
); pp.
, 
2023
.
abstract
pdf
link

Featured News

Quantum Leap Healthcare Collaborative Announces Positive Result of Oral Paclitaxel in Combination with a PD-1 and Carboplatin from I-SPY2 TRIAL in Neoadjuvant Breast CancerQuantum Leap Healthcare Collaborative Announces Positive Result of Oral Paclitaxel in Combination with a PD-1 and Carboplatin from I-SPY2 TRIAL in Neoadjuvant Breast Cancer

Oral Paclitaxel combination regimen has graduated from this Phase 2 trial in the triple negative breast cancer subgroup of the I-SPY2 Trial

Press Release

December 20, 2022

I-SPY updates breast cancer subtypes with response-predictive biomarkers generated across 10 therapiesI-SPY updates breast cancer subtypes with response-predictive biomarkers generated across 10 therapies

I-SPY in the News

June 14, 2022

Esserman brings urgency for ‘learning healthcare’ to learn faster, betterEsserman brings urgency for ‘learning healthcare’ to learn faster, better

I-SPY in the News

June 6, 2022

-- more news --

What is I-SPY?

The I-SPY series of trials are changing the way new treatments are developed for breast cancer, helping make available new, better and more personalized treatments, faster. At the heart of the I-SPY program is the ground-breaking I-SPY 2 platform trial for neoadjuvant treatment of locally advanced breast cancer.

>2500
patients enrolled
25
agents completed
evaluation since 2010
3
agents received
accelerated approval
Find out more

World-class science requires world-class scientists

Meet some of our team
Henry Kaplan
, 
MD
Medical Oncologist
Swedish Cancer Institute
Christina Yau
, 
PhD
Bioinformatician
University of California, San Francisco
Kathleen Kemmer
, 
MD, BA
Medical Oncologist
Oregon Health and Science University
Erica Stringer-Reasor
, 
MD
Medical Oncology
University of Alabama at Birmingham

I-SPY is supported by:

I-SPY Sponsor:
‍
Quantum Leap Healthcare Collaborative

The I-SPY Trials

Sponsored by Quantum Leap Healthcare Collaborative™, a 501C(3) charitable organization accelerating the union of high-impact clinical research and patient care to improve and save lives.

 
Quick Links:
Media CenterCareersInvestigator Login
© 2019  Quantum Leap Healthcare Collaborative