Study Procedures

I-SPY 2 TRIAL Study Procedures

The I-SPY 2 TRIAL is testing investigational drugs as part of chemotherapy treatment before having surgery. The study is also using MRI scans, tissue samples and blood samples to learn more about how women respond to chemotherapy treatment before surgery and how to identify which women will respond best to certain treatments. Below is a diagram of all of the study procedures you will have while you are in this trial:

Study Schedule

Typical treatment for participants spans 32 weeks. The following chart shows a sample study schedule:

Additional Information

The following links describes the study procedures used to learn about your cancer and your response to treatment:

What is Magnetic Resonance Imaging (MRI) scan and why is it being used in I-SPY 2?

What is a biomarker and why is it being used in I-SPY 2?

What is neoadjuvant treatment and why is it being used in I-SPY 2?

What are investigational drugs and why are they being used in I-SPY 2?